Who Framed Roger Rabbit is an action-adventure video game created for the NES by Rare and published by LJN Toys Inc. in 1989. The single-player game is loosely based on the film of the same name and had combined elements of graphic adventure computer games with some more traditional action adventure gameplay. A different version of the game was also released for various computer systems in 1988.

The game takes place in Los Angeles in 1947.

As the game begins the player takes control of Eddie Valliant, with the framed Roger Rabbit cartoon character always following Valiant. The player wanders around an urban city of Hollywood entering various buildings, and caves in order to speak with people, some of whom are from the film, and picks up various items left on the ground and inside drawers and chests in order to find out who framed Roger Rabbit.

The second half of the game takes the player into the infamous Toontown with more buildings and caves to explore in an effort to find Marvin Acme's lost will, and prepare for a battle with the nefarious Judge Doom. During the gameplay, gamers would have to call a phone number. Inside the Ink & Paint Club, initially talking to Jessica Rabbit gives the response "Find my Phone No. and give me a call". If the number was called, it would give the gamers clues as to how to continue gameplay.

Indeed, the player will find a real 1-800 toll-free phone number (1-800-232-3324) . Dialing this number on a real telephone would play a recorded message of Jessica giving tips for the game. As follows is some of what was said in the recording before the number was transferred to another company:

"It is shocking the way some neighborhoods are getting. You practically can't walk anywhere without running into stray dogs, cats, and other animals. It makes you wish you carried a piece of meat, a fish bone, or a piece of cheese around with you. The weasel that is guarding Judge Doom's warehouse is the one called Stupid. I've heard that the only thing that'll get him to leave is a quick game of softball. Know anyplace where you could get a baseball in a hurry?"