Mary Shelley's Frankenstein is a video game for multiple platforms that is based on the 1994 movie of the same name. These systems include the Super Nintendo Entertainment System, the Sega CD and the Sega Genesis.

The player uses a wooden stick to ward off enemies. The stick that Frankenstein's monster carries can be put on fire if swung towards fire. Frankenstein also has an additional attack; a blue ball of negative energy that pops up when the player releases the button. Peasants in the game can either be male or female; soldiers are always male. The female peasants attack with pots while the male peasants attack with melee weapons. However, the soldiers (men dressed in red) attack the player with musket shots. Simple puzzles involving switches and pulleys must be solved in order to progress within the levels.